In the human brain, visuo-haptic (VH) object perception involves a distributed network of functionally connected cortical as well as subcortical regions. In order to investigate directed influences (i.e., effective connectivity) between these regions we applied hypothesis-generating Granger causality mapping (GCM) to an fMRI data set acquired during visual, haptic, and visuo-haptic object perception. Wooden 3D objects (so-called ‘fribbles’) were presented either unimodally (V; H) or bimodally (VH). In addition, we controlled for potential cue and motor confounds using a ‘no-object’ baseline condition (M). Effects of VH integration (M<V<VH>H>M) were found in a network of brain regions including left LOC, bilateral IPS, and the lateral cerebellum, bilaterally. These regions were used as so-called seed regions for subsequent GCM. Preliminary results showed that LOC activation is predicted more reliably during unimodal haptic as compared to unimodal visual stimulation. During bimodal VH stimulation, however, LOC activation is predicted best by several cortical as well as subcortical regions. Based on additional (including hypothesis-testing) analyses we will report comprehensive results for all seed regions used.